Biophotonics '09: Lecture by Prof. Steven L Jacques

Tissue optics

Professor Steven L. Jacques

Steven L. Jacques
Professor, Biomedical Engineering & Dermatology
Oregon Health & Science University
CH13B 3303 SW Bond Avenue, Portland, OR 97239, USA

Biomedical Engineering (13th floor CHH building, waterfront campus)
Tel: +1 503 418 9338 (office in BME)
Tel: +1 503 418 9351 (lab in BME)

Dermatology (Baird 2052, Marquam Hill campus)
Tel: +1 503 494 8066 (office in DERM)
Tel: +1 503 418 2119 (lab in DERM)

E-mail: sjacques@bme.ogi.edu
Web: http://www.bme.ogi.edu/~sjacques

Abstract

The basics of tissue optics will be presented.  The origins of optical properties in tissues are discussed, linking the biological structures encountered in cells and tissues to the optical properties that govern light transport. Imaging and spectroscopic sensing based on absorption, fluorescence, Raman scattering and elastic light scattering are introduced.  The properties of absorption coefficient, scattering coefficient, anisotropy of scattering, and refractive index are discussed. The use of these properties in optical transport theory, including Monte Carlo simulations, diffusion theory, and the Pn method, will be demonstrated. Examples of common optical measurements demonstrate how measured observations are interpreted by theory to specify the tissue optical properties. The influence of optical properties on optical contrast based on absorption, fluorescence or scattering is discussed. The ability to measure optical properties and use these properties in theory to predict optical behavior in experimental situations is a basic skill needed in biomedical optics and biophotonics.

Recommended reading

S. Jacques, B. Pogue, "Tutorial on diffuse light transport," J. Biomedical Optics 13, 041302 (2008).

Link to program

• Session 1

Link to lectures at Biophotonics '09 Lecture 1 Lecture 2 Lecture 3 Lecture 4 Link to lectures at Biophotonics '07 Origins of optical contrast in tissues: Optical properties Origins of optical contrast in tissues: How to measure optical properties Origins of optical contrast in tissues: Light transport Origins of optical contrast in tissues: Complex tissues
	Professor Steven L. Jacques teaching at Biophotonics '07.

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